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PDF - Animation of the intraerythrocytic development cycle based on change of expression rates of the P. falciparum genome

Description: This animation of the intraerythrocytic development cycle is based on change of expression rates of genes on the 14 nuclear chromosomes of P. falciparum HB3 (see also figure 4). The upper left corner displays an `infection timer' which indicates up- (red) and down regulation (blue) of all genes during a certain time point. The genes with strong up (red dots) or down-regulation (blue dots) are indicated. The diameter of the dot indicates the degree of regulation (e.g., large red dot means strong up-regulation).

PDF - Animation of the intraerythrocytic development cycle based on gene activities of the P. falciparum genome

Description: The animation of the intraerythrocytic development cycle is based on gene activities of genes on the 14 nuclear chromosomes of P. falciparum HB3 (see also figure 3). The upper left corner displays an `infection timer' which indicates high (red) and low (green) expression of all genes during a certain time point. The genes with strong (red dots) or weak (green dots) expression are indicated, while the diameter of the dot indicates the expression level (e.g., large green dot means very low expression). As a result we observed that subtelomeric regions show a behaviour which is clearly distinct from central chromosomal regions.